Help and information for mesh users.

Bicarbonate Overdose

GranuFlo and NaturaLyte acid concentrates can increase bicarbonate levels in the blood stream to dangerous heights when used during hemodialysis treatment. A bicarbonate overdose could potentially lead to severe side effects such as metabolic alkalosis, heart attack and stroke.

Dialysate solutions created with GranuFlo and NaturaLyte acid concentrates include sodium diacetate, which the body converts into bicarbonate as a way to neutralize acid buildup in the blood stream of dialysis patients. The sodium acetate in GranuFlo and NaturaLyte is converted into bicarbonate at a faster rate than other dialysate concentrates, which could cause bicarbonate overdoses for patients that already have high pre-dialysis bicarbonate blood levels. Bicarbonate overdoses can result in metabolic alkalosis, which can lead to heart attack, cardiopulmonary arrest, stroke or sudden death.

Fresenius Medical Care (FMC), manufacturer of GranuFlo and NaturaLyte, issued an internal memo to Fresenius dialysis centers warning that the high bicarbonate levels caused by their acid concentrates could increase the risk of heart attack among dialysis patients by up to six times. Fresenius did not issue the same warning to thousands of physicians using GranuFlo and NaturaLyte acid concentrates in dialysis clinics not owned by FMC.

If you or a loved one were injured after receiving dialysis treatment with GranuFlo and NaturaLyte, contact the attorneys at Hissey Kientz, LLP for a free case evaluation. You can reach us by calling toll-free at 1-866-275-4454, or by filling out our free contact form on the right of this page.

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